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The potential therapeutic value and application prospect of engineered exosomes in human diseases
Exosomes are tiny vesicles produced by a wide range of cells that contain complex RNA and protein. In the diagnosis, treatment, and prevention of illness, they offer great potential. In vitro engineering technique modifies exosomes to produce designed exosomes that include nucleic acids, proteins, a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751586/ https://www.ncbi.nlm.nih.gov/pubmed/36531952 http://dx.doi.org/10.3389/fcell.2022.1051380 |
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author | Liu, Gege Wu, Junlu Chen, Guofei Shang, Anquan |
author_facet | Liu, Gege Wu, Junlu Chen, Guofei Shang, Anquan |
author_sort | Liu, Gege |
collection | PubMed |
description | Exosomes are tiny vesicles produced by a wide range of cells that contain complex RNA and protein. In the diagnosis, treatment, and prevention of illness, they offer great potential. In vitro engineering technique modifies exosomes to produce designed exosomes that include nucleic acids, proteins, and medicines, and are targeted to particular tissues or cells. Their applications range from tumor imaging and gene therapy to vaccine production and regenerative medicine to targeted medication delivery. Many disciplines have promising futures for using this technology. In this review, we’ll look at the potential therapeutic usefulness and use of engineered exosomes in a variety of human illnesses with various systemic manifestations. |
format | Online Article Text |
id | pubmed-9751586 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97515862022-12-16 The potential therapeutic value and application prospect of engineered exosomes in human diseases Liu, Gege Wu, Junlu Chen, Guofei Shang, Anquan Front Cell Dev Biol Cell and Developmental Biology Exosomes are tiny vesicles produced by a wide range of cells that contain complex RNA and protein. In the diagnosis, treatment, and prevention of illness, they offer great potential. In vitro engineering technique modifies exosomes to produce designed exosomes that include nucleic acids, proteins, and medicines, and are targeted to particular tissues or cells. Their applications range from tumor imaging and gene therapy to vaccine production and regenerative medicine to targeted medication delivery. Many disciplines have promising futures for using this technology. In this review, we’ll look at the potential therapeutic usefulness and use of engineered exosomes in a variety of human illnesses with various systemic manifestations. Frontiers Media S.A. 2022-12-01 /pmc/articles/PMC9751586/ /pubmed/36531952 http://dx.doi.org/10.3389/fcell.2022.1051380 Text en Copyright © 2022 Liu, Wu, Chen and Shang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cell and Developmental Biology Liu, Gege Wu, Junlu Chen, Guofei Shang, Anquan The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title | The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title_full | The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title_fullStr | The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title_full_unstemmed | The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title_short | The potential therapeutic value and application prospect of engineered exosomes in human diseases |
title_sort | potential therapeutic value and application prospect of engineered exosomes in human diseases |
topic | Cell and Developmental Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751586/ https://www.ncbi.nlm.nih.gov/pubmed/36531952 http://dx.doi.org/10.3389/fcell.2022.1051380 |
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