Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward

Despite the prevalence of opioid misuse, opioids remain the frontline treatment regimen for severe pain. However, opioid safety is hampered by side-effects such as analgesic tolerance, reduced analgesia to neuropathic pain, physical dependence, or reward. These side effects promote development of op...

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Detalles Bibliográficos
Autores principales: Gamble, Mackenzie C., Williams, Benjamin R., Singh, Navsharan, Posa, Luca, Freyberg, Zachary, Logan, Ryan W., Puig, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751598/
https://www.ncbi.nlm.nih.gov/pubmed/36532632
http://dx.doi.org/10.3389/fnsys.2022.1059089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751598/
https://www.ncbi.nlm.nih.gov/pubmed/36532632
http://dx.doi.org/10.3389/fnsys.2022.1059089

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