An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection

We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-P...

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Detalles Bibliográficos
Autores principales: Goto, Ryoji, Kawakami, Haruka, Horiuchi, Yurino, Chikada, Ayaka, Yasuda, Tsutomu, Suzuki, Tetsuya, Miyazato, Yusuke, Ishikane, Masahiro, Kishino, Yuya, Miyazaki, Hideki, Igari, Toru, Katano, Harutaka, Suzuki, Tadaki, Murayama, Shigeo, Arai, Noritoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751720/
https://www.ncbi.nlm.nih.gov/pubmed/36070957
http://dx.doi.org/10.2169/internalmedicine.9726-22
Descripción
Sumario:We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.

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