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An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection
We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-P...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751720/ https://www.ncbi.nlm.nih.gov/pubmed/36070957 http://dx.doi.org/10.2169/internalmedicine.9726-22 |
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author | Goto, Ryoji Kawakami, Haruka Horiuchi, Yurino Chikada, Ayaka Yasuda, Tsutomu Suzuki, Tetsuya Miyazato, Yusuke Ishikane, Masahiro Kishino, Yuya Miyazaki, Hideki Igari, Toru Katano, Harutaka Suzuki, Tadaki Murayama, Shigeo Arai, Noritoshi |
author_facet | Goto, Ryoji Kawakami, Haruka Horiuchi, Yurino Chikada, Ayaka Yasuda, Tsutomu Suzuki, Tetsuya Miyazato, Yusuke Ishikane, Masahiro Kishino, Yuya Miyazaki, Hideki Igari, Toru Katano, Harutaka Suzuki, Tadaki Murayama, Shigeo Arai, Noritoshi |
author_sort | Goto, Ryoji |
collection | PubMed |
description | We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan. |
format | Online Article Text |
id | pubmed-9751720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-97517202022-12-22 An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection Goto, Ryoji Kawakami, Haruka Horiuchi, Yurino Chikada, Ayaka Yasuda, Tsutomu Suzuki, Tetsuya Miyazato, Yusuke Ishikane, Masahiro Kishino, Yuya Miyazaki, Hideki Igari, Toru Katano, Harutaka Suzuki, Tadaki Murayama, Shigeo Arai, Noritoshi Intern Med Case Report We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan. The Japanese Society of Internal Medicine 2022-09-06 2022-11-15 /pmc/articles/PMC9751720/ /pubmed/36070957 http://dx.doi.org/10.2169/internalmedicine.9726-22 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Goto, Ryoji Kawakami, Haruka Horiuchi, Yurino Chikada, Ayaka Yasuda, Tsutomu Suzuki, Tetsuya Miyazato, Yusuke Ishikane, Masahiro Kishino, Yuya Miyazaki, Hideki Igari, Toru Katano, Harutaka Suzuki, Tadaki Murayama, Shigeo Arai, Noritoshi An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title | An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title_full | An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title_fullStr | An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title_full_unstemmed | An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title_short | An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection |
title_sort | autopsy report of a case with cerebral infarction complicated by coronavirus disease 2019 infection |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751720/ https://www.ncbi.nlm.nih.gov/pubmed/36070957 http://dx.doi.org/10.2169/internalmedicine.9726-22 |
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