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605. Efficacy and pharmacokinetics-pharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis

BACKGROUND: Cryptococcal meningitis (CM) is a fungal disease with significant global morbidity and mortality. There are multiple new therapies being developed to improve the current regimens involving amphotericin B, flucytosine, and fluconazole. ATI-2307 is a novel arylamidine which inhibits mitoch...

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Detalles Bibliográficos
Autores principales:	Giamberardino, Charles D, Tenor, Jennifer L, Toffaletti, Dena, Palmucci, Julia R, Cilla, Don, Hope, William, Perfect, John R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751753/ http://dx.doi.org/10.1093/ofid/ofac492.657

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