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Association between lower body temperature and increased tau pathology in cognitively normal older adults

BACKGROUND: Preclinical studies suggest body temperature (Tb) and consequently brain temperature has the potential to bidirectionally interact with tau pathology in Alzheimer’s Disease (AD). Tau phosphorylation is substantially increased by a small (<1 °C) decrease in temperature within the human...

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Detalles Bibliográficos
Autores principales:	Blessing, Esther M., Parekh, Ankit, Betensky, Rebecca A., Babb, James, Saba, Natalie, Debure, Ludovic, Varga, Andrew W., Ayappa, Indu, Rapoport, David M., Butler, Tracy A., de Leon, Mony J., Wisniewski, Thomas, Lopresti, Brian J., Osorio, Ricardo S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751849/ https://www.ncbi.nlm.nih.gov/pubmed/35550158 http://dx.doi.org/10.1016/j.nbd.2022.105748

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