492. Dectin-1 Stimulation Promotes a Distinct Inflammatory Signature in the Setting of Aging and HIV-infection

BACKGROUND: Dectin-1 is an innate immune pattern recognition receptor that recognizes and binds b-1,3/1,6 glucans on fungal pathogens. METHODS: We evaluated Dectin-1 function in innate immune cells (Monocytes and Dendritic cells) in a cohort of HIV-positive and HIV-negative young and older adults (n...

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Autores principales: Zapata, Heidi, Kumar, Archit, Wang, Jiawei, Shaw, Albert, Zhou, Haowen, Radcliffe, Christopher, Barakat, Lydia A, Wyk, Brent Vander, Allore, Heather, Zhao, Hongyu, Tsang, Sui, Manager, Data, Mohanty, Subhasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
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Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751937/
http://dx.doi.org/10.1093/ofid/ofac492.550

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