Endocannabinoid signaling regulates post-operative delirium through glutamatergic mediodorsal thalamus-prelimbic prefrontal cortical projection

BACKGROUND: Post-operative delirium (POD), a common post-operative complication that affects up to 73. 5% of surgical patients, could prolong hospital stays, triple mortality rates, cause long-term cognitive decline and dementia, and boost medical expenses. However, the underlying mechanisms, especi...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Jia, Sansan, Wang, Jiajia, Wang, Dan, Zhang, Xinxin, Liu, Huiqing, Zhou, Fang, Zhang, Zhihao, Li, Qi, Dong, Hailong, Zhong, Haixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752096/
https://www.ncbi.nlm.nih.gov/pubmed/36533179
http://dx.doi.org/10.3389/fnagi.2022.1036428

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