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1153. Safety and Potential Efficacy of Exosomes Overexpressing CD24 (EXO-CD24) for the Prevention of Clinical Deterioration in Patients with Moderate or Severe COVID-19: A Phase II, Randomized, Single-blinded Study.
BACKGROUND: EXO-CD24 is a novel inhaled drug of exosomes displaying CD24, a protein with anti-inflammatory properties. We evaluated the safety and potential efficacy of EXO-CD24, in a phase II, randomized, single-blinded clinical trial of EXO-CD24 in hospitalized patients with moderate or severe COV...
Autores principales: | Grigoropoulos, Ioannis, Tsioulos, Georgios, Kastrissianakis, Artemis, Shapira, Shiran, Arber, Nadir, Poulakou, Garyfallia, Syrigos, Konstantinos, Rapti, Vasiliki, Xynogalas, Ioannis, Leontis, Konstantinos, Ntousopoulos, Vasileios, Sakka, Vissaria, Gaga, Mina, Sardelis, Zafeiris, Fotiadis, Andreas, Vlassi, Lamprini, Kontogianni, Chrysoula, Levounets, Anastasia, Tsakona, Maria, Savva, Athina, Kavatha, Dimitra, Boumpas, Dimitrios, Antoniadou, Anastasia, Tsiodras, Sotirios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752112/ http://dx.doi.org/10.1093/ofid/ofac492.991 |
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