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Intra‐abdominal abscesses in CD – When to treat with biologics?

Management of intra‐abdominal abscesses complicating Crohn's disease (CD) is challenging. After initial drainage and antibiotherapy treatment, surgery with delayed intestinal resection is often recommended but new data suggests efficacy of biotherapies in this context. This review aims to summa...

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Detalles Bibliográficos
Autores principales: Haas, Manon, Treton, Xavier, Stefanescu, Carmen, Bouhnik, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752265/
https://www.ncbi.nlm.nih.gov/pubmed/36479929
http://dx.doi.org/10.1002/ueg2.12342
Descripción
Sumario:Management of intra‐abdominal abscesses complicating Crohn's disease (CD) is challenging. After initial drainage and antibiotherapy treatment, surgery with delayed intestinal resection is often recommended but new data suggests efficacy of biotherapies in this context. This review aims to summarize new data regarding efficacy and safety of anti‐TNF in the management of intra‐abdominal abscesses complicating CD. We performed a review of the literature on medical management of intra‐abdominal abscesses complicating CD. After effective drainage of abscess, treatment with anti‐TNF can allow resolving of abscess. In some patients and at a specific timing, the use of biotherapies could avoid delayed surgery and long‐term abscess recurrence.