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Intra‐abdominal abscesses in CD – When to treat with biologics?

Management of intra‐abdominal abscesses complicating Crohn's disease (CD) is challenging. After initial drainage and antibiotherapy treatment, surgery with delayed intestinal resection is often recommended but new data suggests efficacy of biotherapies in this context. This review aims to summa...

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Autores principales: Haas, Manon, Treton, Xavier, Stefanescu, Carmen, Bouhnik, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752265/
https://www.ncbi.nlm.nih.gov/pubmed/36479929
http://dx.doi.org/10.1002/ueg2.12342
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author Haas, Manon
Treton, Xavier
Stefanescu, Carmen
Bouhnik, Yoram
author_facet Haas, Manon
Treton, Xavier
Stefanescu, Carmen
Bouhnik, Yoram
author_sort Haas, Manon
collection PubMed
description Management of intra‐abdominal abscesses complicating Crohn's disease (CD) is challenging. After initial drainage and antibiotherapy treatment, surgery with delayed intestinal resection is often recommended but new data suggests efficacy of biotherapies in this context. This review aims to summarize new data regarding efficacy and safety of anti‐TNF in the management of intra‐abdominal abscesses complicating CD. We performed a review of the literature on medical management of intra‐abdominal abscesses complicating CD. After effective drainage of abscess, treatment with anti‐TNF can allow resolving of abscess. In some patients and at a specific timing, the use of biotherapies could avoid delayed surgery and long‐term abscess recurrence.
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spelling pubmed-97522652022-12-19 Intra‐abdominal abscesses in CD – When to treat with biologics? Haas, Manon Treton, Xavier Stefanescu, Carmen Bouhnik, Yoram United European Gastroenterol J Inflammatory Bowel Disease Management of intra‐abdominal abscesses complicating Crohn's disease (CD) is challenging. After initial drainage and antibiotherapy treatment, surgery with delayed intestinal resection is often recommended but new data suggests efficacy of biotherapies in this context. This review aims to summarize new data regarding efficacy and safety of anti‐TNF in the management of intra‐abdominal abscesses complicating CD. We performed a review of the literature on medical management of intra‐abdominal abscesses complicating CD. After effective drainage of abscess, treatment with anti‐TNF can allow resolving of abscess. In some patients and at a specific timing, the use of biotherapies could avoid delayed surgery and long‐term abscess recurrence. John Wiley and Sons Inc. 2022-12-08 /pmc/articles/PMC9752265/ /pubmed/36479929 http://dx.doi.org/10.1002/ueg2.12342 Text en © 2022 The Authors. United European Gastroenterology Journal published by Wiley Periodicals LLC on behalf of United European Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Inflammatory Bowel Disease
Haas, Manon
Treton, Xavier
Stefanescu, Carmen
Bouhnik, Yoram
Intra‐abdominal abscesses in CD – When to treat with biologics?
title Intra‐abdominal abscesses in CD – When to treat with biologics?
title_full Intra‐abdominal abscesses in CD – When to treat with biologics?
title_fullStr Intra‐abdominal abscesses in CD – When to treat with biologics?
title_full_unstemmed Intra‐abdominal abscesses in CD – When to treat with biologics?
title_short Intra‐abdominal abscesses in CD – When to treat with biologics?
title_sort intra‐abdominal abscesses in cd – when to treat with biologics?
topic Inflammatory Bowel Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752265/
https://www.ncbi.nlm.nih.gov/pubmed/36479929
http://dx.doi.org/10.1002/ueg2.12342
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