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1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia

BACKGROUND: According to previous epidemiological studies there is 2.4% prevalence of anti-HCV in Latvian population. Hepatitis C can lead to liver cirrhosis and HCC. There is available an effective HCV treatment with 100% reimbursement. WHO has settled a goal – to eliminate HCV as a public health t...

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Autores principales: Tolmane, Ieva, Upmace, Inga, Azina, Inga, Rozentale, Baiba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752307/
http://dx.doi.org/10.1093/ofid/ofac492.1067
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author Tolmane, Ieva
Upmace, Inga
Azina, Inga
Rozentale, Baiba
author_facet Tolmane, Ieva
Upmace, Inga
Azina, Inga
Rozentale, Baiba
author_sort Tolmane, Ieva
collection PubMed
description BACKGROUND: According to previous epidemiological studies there is 2.4% prevalence of anti-HCV in Latvian population. Hepatitis C can lead to liver cirrhosis and HCC. There is available an effective HCV treatment with 100% reimbursement. WHO has settled a goal – to eliminate HCV as a public health threat by 2030. The biggest obstacle to achieve this goal is to find an infected persons. The aim of this study was to screen and analyze the data of patients from Psychiatry hospitals (PH) in Latvia. Patients were screened for hepatitis C infection (anti-HCV) and analyze the possible risk factors. METHODS: 795 patients of all PH in Latvia were tested, including 57.1% males and 42.9% females. The mean age was 49 years (range 18 - 93). Data were obtained by performing survey and rapid blood antibody tests. The questionnaire included demographic information and 10 questions on infection risk factors. Study was done from May till October 2021 by HIV Prevention Point workers in PHs of 7 PH in Latvia – Riga, Daugavpils, Liepaja, Strenci, Gintermuiza, Akniste and Vecpiebalga. Data were analyzed using MS Excel and IBM SPSS. RESULTS: 24.8% of patients noted they have been sexually active in the last year, but only 9.9% admitted usage of condoms. 3.8% noted they are or have been used IV drugs. 11.2% of patients have a history of incarceration. In total 6.8% of performed tests were positive for anti-HCV. Incarcerated persons were positive in 16% of cases, non-incarcerated – in 6%. IV drug users (IVDU) were positive in 49%, non-users – in 4.9%, all differences are statistically significant. CONCLUSION: Patients in PH are at higher risk of HCV infection in comparison to population in Latvia. Besides already well known risk groups – IVDU and incarcerated people, we found 2.8 times higher anti-HCV prevalence in psychiatric hospital’s patients, with markedly higher prevalence in those previously incarcerated or IVDU. This study provides valuable data to better identify groups of individuals with higher risk of HCV infection. Latvia. PNC patients should further be tested, especially individuals who have been incarcerated, use or have used IV drugs. DISCLOSURES: All Authors: No reported disclosures.
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spelling pubmed-97523072022-12-16 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia Tolmane, Ieva Upmace, Inga Azina, Inga Rozentale, Baiba Open Forum Infect Dis Abstracts BACKGROUND: According to previous epidemiological studies there is 2.4% prevalence of anti-HCV in Latvian population. Hepatitis C can lead to liver cirrhosis and HCC. There is available an effective HCV treatment with 100% reimbursement. WHO has settled a goal – to eliminate HCV as a public health threat by 2030. The biggest obstacle to achieve this goal is to find an infected persons. The aim of this study was to screen and analyze the data of patients from Psychiatry hospitals (PH) in Latvia. Patients were screened for hepatitis C infection (anti-HCV) and analyze the possible risk factors. METHODS: 795 patients of all PH in Latvia were tested, including 57.1% males and 42.9% females. The mean age was 49 years (range 18 - 93). Data were obtained by performing survey and rapid blood antibody tests. The questionnaire included demographic information and 10 questions on infection risk factors. Study was done from May till October 2021 by HIV Prevention Point workers in PHs of 7 PH in Latvia – Riga, Daugavpils, Liepaja, Strenci, Gintermuiza, Akniste and Vecpiebalga. Data were analyzed using MS Excel and IBM SPSS. RESULTS: 24.8% of patients noted they have been sexually active in the last year, but only 9.9% admitted usage of condoms. 3.8% noted they are or have been used IV drugs. 11.2% of patients have a history of incarceration. In total 6.8% of performed tests were positive for anti-HCV. Incarcerated persons were positive in 16% of cases, non-incarcerated – in 6%. IV drug users (IVDU) were positive in 49%, non-users – in 4.9%, all differences are statistically significant. CONCLUSION: Patients in PH are at higher risk of HCV infection in comparison to population in Latvia. Besides already well known risk groups – IVDU and incarcerated people, we found 2.8 times higher anti-HCV prevalence in psychiatric hospital’s patients, with markedly higher prevalence in those previously incarcerated or IVDU. This study provides valuable data to better identify groups of individuals with higher risk of HCV infection. Latvia. PNC patients should further be tested, especially individuals who have been incarcerated, use or have used IV drugs. DISCLOSURES: All Authors: No reported disclosures. Oxford University Press 2022-12-15 /pmc/articles/PMC9752307/ http://dx.doi.org/10.1093/ofid/ofac492.1067 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstracts
Tolmane, Ieva
Upmace, Inga
Azina, Inga
Rozentale, Baiba
1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title_full 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title_fullStr 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title_full_unstemmed 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title_short 1235. Anti-HCV Prevalence and Associated Risk Factors in Patients of Psychiatry Hospitals in Latvia
title_sort 1235. anti-hcv prevalence and associated risk factors in patients of psychiatry hospitals in latvia
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752307/
http://dx.doi.org/10.1093/ofid/ofac492.1067
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