1722. In vivo Activity of Imipenem/XNW4107 Human-Simulated Regimen against Serine Carbapenemase-Producing Acinetobacter baumannii and Pseudomonas aeruginosa in the Neutropenic Murine Thigh Infection Model

BACKGROUND: Imipenem (IPM)/XNW4107 is a novel β-lactam/β-lactamase inhibitor with in vitro activity against serine carbapenemase-producing Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales. Herein, we evaluated the in vivo activity of an IPM/XNW4107 human-simulated regimen (HSR) a...

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Detalles Bibliográficos
Autores principales: Fratoni, Andrew J, Berry, Angela, Yuan, Haitao, Liu, Xiao, Chen, Xi, Wu, Yuchuan, Nicolau, David P, Abdelraouf, Kamilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752493/
http://dx.doi.org/10.1093/ofid/ofac492.1352

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