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1057. Development of a Flow Cytometry-Based Micro-Neutralisation Assay to Evaluate Humoral Immunity Against SARS-CoV-2 Variants of Concern in Vaccine Trials

BACKGROUND: Quantifying neutralising capacity of circulating SARS-COV-2 antibodies is critical in evaluating protective humoral immune responses generated post-infection/post-vaccination. Here we describe a novel medium-throughput flow cytometry based micro-neutralisation assay to evaluate Neutralis...

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Detalles Bibliográficos
Autores principales: O’Reilly, Sophie R, Kenny, Grace, Alrawahneh, Tamara, Francois, Nathan, Angeliadis, Matthew, de Masson d’Autume, Valentin, Garcia-Leon, Alejandro, Feeney, Eoin, Yousif, Obada, Cotter, Aoife, de Barra, Eoghan, Horgan, Mary, Mallon, Patrick, BCh, M B, Gautier, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752580/
http://dx.doi.org/10.1093/ofid/ofac492.898