628. Utilizing Cefepime Therapeutic Drug Monitoring for Patients at Risk of or Exhibiting Signs of Neurotoxicity

BACKGROUND: Increasing risk of neurotoxicity has been observed with increasing cefepime levels, potentially due to the competitive inhibition of GABA receptors in the central nervous system (CNS). The suggested threshold is ≥20 mg/dL. Risk factors include decreased clearance with renal impairment, o...

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Detalles Bibliográficos
Autores principales: Au, Joanna, Jain, Sumeet, Lin, Amanda, Luo, Evelyn, Gautam-Goyal, Pranisha, Saunders-Hao, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752893/
http://dx.doi.org/10.1093/ofid/ofac492.680

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