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Viral origin of eukaryotic type IIA DNA topoisomerases

Type II DNA topoisomerases of the family A (Topo IIAs) are present in all Bacteria (DNA gyrase) and eukaryotes. In eukaryotes, they play a major role in transcription, DNA replication, chromosome segregation, and modulation of chromosome architecture. The origin of eukaryotic Topo IIA remains myster...

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Detalles Bibliográficos
Autores principales: Guglielmini, Julien, Gaia, Morgan, Da Cunha, Violette, Criscuolo, Alexis, Krupovic, Mart, Forterre, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9752973/
https://www.ncbi.nlm.nih.gov/pubmed/36533149
http://dx.doi.org/10.1093/ve/veac097