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Investigation of the Effect of Turn Residues on Tetrapeptide Aldol Catalysts with β-Turn Propensity

[Image: see text] Peptide catalysts for a wide diversity of reaction types contain a common motif—residues that bias the sequence toward β-turn secondary structure. In this work, we explore what role that secondary structure plays in the catalysis of aldol reactions for primary amine tetrapeptide al...

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Detalles Bibliográficos
Autores principales: Liu, Albert Y., Calicdan, Xavier A., Glover, Gene N., Luo, Xue, Barroso, Gage T., Hoppe, Brooke K., Boyle, Kelsey M., Witus, Leah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753199/
https://www.ncbi.nlm.nih.gov/pubmed/36530262
http://dx.doi.org/10.1021/acsomega.2c05921