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Rationale and protocol design of a phase II study of first-line osimertinib treatment for patients with poor performance status and EGFR mutation-positive non-small cell lung cancer (OPEN/TORG2040)
BACKGROUND: Cancer chemotherapy indications for patients with poor performance status and advanced lung cancer are limited. Molecular targeted drugs, including epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors, can be used in patients with poor performance status owing to their high...
Autores principales: | Fukui, Tomoya, Sasaki, Jiichiro, Igawa, Satoshi, Kada, Akiko, Saito, Toshiki I., Kogure, Yoshihito, Okamoto, Hiroaki, Naoki, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753257/ https://www.ncbi.nlm.nih.gov/pubmed/36522630 http://dx.doi.org/10.1186/s12885-022-10409-6 |
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