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Deferiprone, an iron chelator, alleviates platelet hyperactivity in patients with β-thalassaemia/HbE

BACKGROUND: Hyperfunctional platelets play important roles in thromboembolism in patients with β-thalassaemia/ haemoglobin E (β-thal/HbE). Our previous study revealed ex vivo inhibitory effects of deferiprone on normal platelets. Herein, we aimed to investigate the in vivo effects on platelets in pa...

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Detalles Bibliográficos
Autores principales: Tran, Ngan Thi, Sutcharitchan, Pranee, Janprasit, Jindaporn, Rojnuckarin, Ponlapat, Morales, Noppawan Phumala, Luechapudiporn, Rataya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753601/
https://www.ncbi.nlm.nih.gov/pubmed/36544626
http://dx.doi.org/10.7573/dic.2022-7-6