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The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1
Antibiotic Resistance (ABR) is a global concern and while many students are aware of this issue, many of them are unclear on the mechanisms by which ABR may emerge. The mechanism of horizontal gene transfer is something many students are not familiar with. In this curriculum contribution we present...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753655/ https://www.ncbi.nlm.nih.gov/pubmed/36532220 http://dx.doi.org/10.1128/jmbe.00125-22 |
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author | Boury, N. Van den Bogaard, M. E. D. Wasendorf, C. Amon, J. Judson, S. Maroushek, S. R. Peters, N. T. |
author_facet | Boury, N. Van den Bogaard, M. E. D. Wasendorf, C. Amon, J. Judson, S. Maroushek, S. R. Peters, N. T. |
author_sort | Boury, N. |
collection | PubMed |
description | Antibiotic Resistance (ABR) is a global concern and while many students are aware of this issue, many of them are unclear on the mechanisms by which ABR may emerge. The mechanism of horizontal gene transfer is something many students are not familiar with. In this curriculum contribution we present 2 versions of an ‘interrupted case study’ that is designed as an introduction to horizontal gene transfer for early major students and as a review case for advanced major students in biology and life sciences. The case is based on an authentic patient who developed infections with both methicillin resistant Staphylococcus aureus and vancomycin resistant S. aureus. The interrupted case study is appropriate for small and large groups and engages students while content is introduced in a highly structured way. This type of case study can be done by novice and seasoned instructors and lead to considerable learning gains in both introductory and intermediate microbiology courses. |
format | Online Article Text |
id | pubmed-9753655 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | American Society for Microbiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-97536552022-12-16 The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 Boury, N. Van den Bogaard, M. E. D. Wasendorf, C. Amon, J. Judson, S. Maroushek, S. R. Peters, N. T. J Microbiol Biol Educ Curriculum Antibiotic Resistance (ABR) is a global concern and while many students are aware of this issue, many of them are unclear on the mechanisms by which ABR may emerge. The mechanism of horizontal gene transfer is something many students are not familiar with. In this curriculum contribution we present 2 versions of an ‘interrupted case study’ that is designed as an introduction to horizontal gene transfer for early major students and as a review case for advanced major students in biology and life sciences. The case is based on an authentic patient who developed infections with both methicillin resistant Staphylococcus aureus and vancomycin resistant S. aureus. The interrupted case study is appropriate for small and large groups and engages students while content is introduced in a highly structured way. This type of case study can be done by novice and seasoned instructors and lead to considerable learning gains in both introductory and intermediate microbiology courses. American Society for Microbiology 2022-11-16 /pmc/articles/PMC9753655/ /pubmed/36532220 http://dx.doi.org/10.1128/jmbe.00125-22 Text en Copyright © 2022 Boury et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International license (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Curriculum Boury, N. Van den Bogaard, M. E. D. Wasendorf, C. Amon, J. Judson, S. Maroushek, S. R. Peters, N. T. The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title | The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title_full | The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title_fullStr | The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title_full_unstemmed | The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title_short | The Use of a Multimodal Case Study To Illustrate Microbial Genetics, Metabolism, and Evolution: The Emergence of VRSA-1 |
title_sort | use of a multimodal case study to illustrate microbial genetics, metabolism, and evolution: the emergence of vrsa-1 |
topic | Curriculum |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753655/ https://www.ncbi.nlm.nih.gov/pubmed/36532220 http://dx.doi.org/10.1128/jmbe.00125-22 |
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