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Small Interfering RNAs Targeting a Chromatin-Associated RNA Induce Its Transcriptional Silencing in Human Cells

Transcriptional gene silencing by small interfering RNAs (siRNAs) has been widely described in various species, including plants and yeast. In mammals, its extent remains somewhat debated. Previous studies showed that siRNAs targeting gene promoters could induce the silencing of the targeted promote...

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Detalles Bibliográficos
Autores principales:	Ouvrard, Julien, Muniz, Lisa, Nicolas, Estelle, Trouche, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753735/ https://www.ncbi.nlm.nih.gov/pubmed/36445136 http://dx.doi.org/10.1128/mcb.00271-22

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