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Can HIV vaccines be shared fairly? Perspectives from Tanzania

BACKGROUND: For over 35 years, Africa has continued to host HIV vaccine trials geared towards overturning the HIV/AIDs pandemic in the continent. However, the methods of sharing the vaccines, when available remain less certain. Therefore, the study aims to explore stakeholders’ perspectives in the g...

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Autores principales: Pancras, Godwin, Ezekiel, Mangi, Nderitu, David, Mbugi, Erasto, Merz, Jon F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753866/
https://www.ncbi.nlm.nih.gov/pubmed/36522782
http://dx.doi.org/10.1186/s12910-022-00874-w
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author Pancras, Godwin
Ezekiel, Mangi
Nderitu, David
Mbugi, Erasto
Merz, Jon F.
author_facet Pancras, Godwin
Ezekiel, Mangi
Nderitu, David
Mbugi, Erasto
Merz, Jon F.
author_sort Pancras, Godwin
collection PubMed
description BACKGROUND: For over 35 years, Africa has continued to host HIV vaccine trials geared towards overturning the HIV/AIDs pandemic in the continent. However, the methods of sharing the vaccines, when available remain less certain. Therefore, the study aims to explore stakeholders’ perspectives in the global South, in this case, Tanzania, on how HIV vaccines ought to be fairly shared. METHODS: The study deployed a qualitative case study design. Data were collected through in-depth interviews and focus group discussions with a total of 37 purposively selected participants. This included researchers, institutional review board members, a policymaker, HIV/AIDS advocates, and community advisory board members. The data obtained were inductively and deductively analyzed. RESULTS: Findings indicate that HIV vaccines can be shared fairly under the principles of distributive justice (contribution, need and equality). Thus, contribution-based sharing ought to be utilized upon the necessity to prioritize vaccine access or subsidized trial benefits to host communities. Need-based sharing ought to be considered for non-host communities that are at an increased risk of HIV infection. Lastly, equal-based sharing would be useful at later stages of vaccine distribution or when the aforementioned principles are deemed morally inappropriate. However, none of the benefit-sharing approaches is free of limitations and a counterbalancing sense of unfairness. CONCLUSION: Fair sharing of HIV vaccines, when available, ought to be informed by the contribution, need and equality principles of distributive justice. Countries in the global south including Tanzania are likely to be prioritized during the distribution of the HIV vaccines due to their participation in HIV vaccine trials and due to the disproportionate HIV burden evident in the region.
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spelling pubmed-97538662022-12-15 Can HIV vaccines be shared fairly? Perspectives from Tanzania Pancras, Godwin Ezekiel, Mangi Nderitu, David Mbugi, Erasto Merz, Jon F. BMC Med Ethics Research BACKGROUND: For over 35 years, Africa has continued to host HIV vaccine trials geared towards overturning the HIV/AIDs pandemic in the continent. However, the methods of sharing the vaccines, when available remain less certain. Therefore, the study aims to explore stakeholders’ perspectives in the global South, in this case, Tanzania, on how HIV vaccines ought to be fairly shared. METHODS: The study deployed a qualitative case study design. Data were collected through in-depth interviews and focus group discussions with a total of 37 purposively selected participants. This included researchers, institutional review board members, a policymaker, HIV/AIDS advocates, and community advisory board members. The data obtained were inductively and deductively analyzed. RESULTS: Findings indicate that HIV vaccines can be shared fairly under the principles of distributive justice (contribution, need and equality). Thus, contribution-based sharing ought to be utilized upon the necessity to prioritize vaccine access or subsidized trial benefits to host communities. Need-based sharing ought to be considered for non-host communities that are at an increased risk of HIV infection. Lastly, equal-based sharing would be useful at later stages of vaccine distribution or when the aforementioned principles are deemed morally inappropriate. However, none of the benefit-sharing approaches is free of limitations and a counterbalancing sense of unfairness. CONCLUSION: Fair sharing of HIV vaccines, when available, ought to be informed by the contribution, need and equality principles of distributive justice. Countries in the global south including Tanzania are likely to be prioritized during the distribution of the HIV vaccines due to their participation in HIV vaccine trials and due to the disproportionate HIV burden evident in the region. BioMed Central 2022-12-15 /pmc/articles/PMC9753866/ /pubmed/36522782 http://dx.doi.org/10.1186/s12910-022-00874-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Pancras, Godwin
Ezekiel, Mangi
Nderitu, David
Mbugi, Erasto
Merz, Jon F.
Can HIV vaccines be shared fairly? Perspectives from Tanzania
title Can HIV vaccines be shared fairly? Perspectives from Tanzania
title_full Can HIV vaccines be shared fairly? Perspectives from Tanzania
title_fullStr Can HIV vaccines be shared fairly? Perspectives from Tanzania
title_full_unstemmed Can HIV vaccines be shared fairly? Perspectives from Tanzania
title_short Can HIV vaccines be shared fairly? Perspectives from Tanzania
title_sort can hiv vaccines be shared fairly? perspectives from tanzania
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753866/
https://www.ncbi.nlm.nih.gov/pubmed/36522782
http://dx.doi.org/10.1186/s12910-022-00874-w
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