The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation

The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequen...

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Detalles Bibliográficos
Autores principales: Liu, Wendao, Ye, Xiaohua, An, Zhiqiang, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753867/
https://www.ncbi.nlm.nih.gov/pubmed/36522785
http://dx.doi.org/10.1186/s12985-022-01923-x
Descripción
Sumario:The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.

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