The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation

The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequen...

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Autores principales: Liu, Wendao, Ye, Xiaohua, An, Zhiqiang, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753867/
https://www.ncbi.nlm.nih.gov/pubmed/36522785
http://dx.doi.org/10.1186/s12985-022-01923-x
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author Liu, Wendao
Ye, Xiaohua
An, Zhiqiang
Zhao, Zhongming
author_facet Liu, Wendao
Ye, Xiaohua
An, Zhiqiang
Zhao, Zhongming
author_sort Liu, Wendao
collection PubMed
description The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases.
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spelling pubmed-97538672022-12-15 The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation Liu, Wendao Ye, Xiaohua An, Zhiqiang Zhao, Zhongming Virol J Comment The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, we discuss the current challenges, limitations, and perspectives in harnessing the power of single-cell RNA sequencing to accelerate both basic research and therapeutic development for COVID-19 and other emerging infectious diseases. BioMed Central 2022-12-15 /pmc/articles/PMC9753867/ /pubmed/36522785 http://dx.doi.org/10.1186/s12985-022-01923-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Comment
Liu, Wendao
Ye, Xiaohua
An, Zhiqiang
Zhao, Zhongming
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title_full The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title_fullStr The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title_full_unstemmed The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title_short The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
title_sort challenges and opportunities of scrna-seq in covid-19 research and clinical translation
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753867/
https://www.ncbi.nlm.nih.gov/pubmed/36522785
http://dx.doi.org/10.1186/s12985-022-01923-x
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