Absence of proximal muscle weakness, dysarthria, and facial diplegia suggests Guillain–Barre syndrome rather than CIDP

The aim of this letter to the editor is to discuss the etiology and pathophysiology of chronic inflammatory demyelinating polyneuropathy (CIDP) in two patients, of whom one experienced a mildly symptomatic SARS-CoV-2 infection 2 months prior to onset of the CIDP (patient-1), whereas patient-2 developed CIDP with bilateral facial palsy 19 days after receiving a shot of an RNA-based anti-SARS-CoV-2 vaccine. Causality between the SARS-CoV-2 infection and CIDP in patient-1 remains unsupported and the diagnosis CIDP in patient-2 remains questionable. Although delineation between CIDP and GBS is not clear cut, bilateral facial palsy and absence of proximal involvement suggest GBS rather than CIDP.