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Cellular functions of the ClpP protease impacting bacterial virulence

Proteostasis mechanisms significantly contribute to the sculpting of the proteomes of all living organisms. ClpXP is a central AAA+ chaperone-protease complex present in both prokaryotes and eukaryotes that facilitates the unfolding and subsequent degradation of target substrates. ClpX is a hexameri...

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Detalles Bibliográficos
Autores principales: Aljghami, Mazen E., Barghash, Marim M., Majaesic, Emily, Bhandari, Vaibhav, Houry, Walid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753991/
https://www.ncbi.nlm.nih.gov/pubmed/36533084
http://dx.doi.org/10.3389/fmolb.2022.1054408