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TIAM1-mediated synaptic plasticity underlies comorbid depression–like and ketamine antidepressant–like actions in chronic pain

Chronic pain often leads to depression, increasing patient suffering and worsening prognosis. While hyperactivity of the anterior cingulate cortex (ACC) appears to be critically involved, the molecular mechanisms underlying comorbid depressive symptoms in chronic pain remain elusive. T cell lymphoma...

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Detalles Bibliográficos
Autores principales:	Ru, Qin, Lu, Yungang, Saifullah, Ali Bin, Blanco, Francisco A., Yao, Changqun, Cata, Juan P., Li, De-Pei, Tolias, Kimberley F., Li, Lingyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9753999/ https://www.ncbi.nlm.nih.gov/pubmed/36519542 http://dx.doi.org/10.1172/JCI158545

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