Potential binding modes of the gut bacterial metabolite, 5-hydroxyindole, to the intestinal L-type calcium channels and its impact on the microbiota in rats

Intestinal microbiota and microbiota-derived metabolites play a key role in regulating the host physiology. Recently, we have identified a gut-bacterial metabolite, namely 5-hydroxyindole, as a potent stimulant of intestinal motility via its modulation of L-type voltage-gated calcium channels locate...

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Detalles Bibliográficos
Autores principales: Waclawiková, Barbora, Cesar Telles de Souza, Paulo, Schwalbe, Markus, Neochoritis, Constantinos G., Hoornenborg, Warner, Nelemans, Sieger A., Marrink, Siewert J., El Aidy, Sahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754111/
https://www.ncbi.nlm.nih.gov/pubmed/36511640
http://dx.doi.org/10.1080/19490976.2022.2154544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754111/
https://www.ncbi.nlm.nih.gov/pubmed/36511640
http://dx.doi.org/10.1080/19490976.2022.2154544

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