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Potential binding modes of the gut bacterial metabolite, 5-hydroxyindole, to the intestinal L-type calcium channels and its impact on the microbiota in rats
Intestinal microbiota and microbiota-derived metabolites play a key role in regulating the host physiology. Recently, we have identified a gut-bacterial metabolite, namely 5-hydroxyindole, as a potent stimulant of intestinal motility via its modulation of L-type voltage-gated calcium channels locate...
Autores principales: | Waclawiková, Barbora, Cesar Telles de Souza, Paulo, Schwalbe, Markus, Neochoritis, Constantinos G., Hoornenborg, Warner, Nelemans, Sieger A., Marrink, Siewert J., El Aidy, Sahar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754111/ https://www.ncbi.nlm.nih.gov/pubmed/36511640 http://dx.doi.org/10.1080/19490976.2022.2154544 |
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