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Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto-1,2,4-triazole

Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay. The synthesized series of azomethines exhibited promising efficacy against liver cancer cell line. Screening of the synthesize...

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Detalles Bibliográficos
Autores principales:	Shahzadi, Irum, Zahoor, Ameer Fawad, Tüzün, Burak, Mansha, Asim, Anjum, Muhammad Naveed, Rasul, Azhar, Irfan, Ali, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754256/ https://www.ncbi.nlm.nih.gov/pubmed/36520942 http://dx.doi.org/10.1371/journal.pone.0278027

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