Recent advances on human mpox

Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies s...

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Autores principales: Orassay, Aliya, Berdigaliyev, Alan, Sadvokassova, Darya, Diassova, Ansal, Amin, Amr, Cao, Wenwen, Xie, Yingqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754762/
https://www.ncbi.nlm.nih.gov/pubmed/36573212
http://dx.doi.org/10.1016/j.nmni.2022.101066
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author Orassay, Aliya
Berdigaliyev, Alan
Sadvokassova, Darya
Diassova, Ansal
Amin, Amr
Cao, Wenwen
Xie, Yingqiu
author_facet Orassay, Aliya
Berdigaliyev, Alan
Sadvokassova, Darya
Diassova, Ansal
Amin, Amr
Cao, Wenwen
Xie, Yingqiu
author_sort Orassay, Aliya
collection PubMed
description Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention.
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spelling pubmed-97547622022-12-22 Recent advances on human mpox Orassay, Aliya Berdigaliyev, Alan Sadvokassova, Darya Diassova, Ansal Amin, Amr Cao, Wenwen Xie, Yingqiu New Microbes New Infect Original Article Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention. Elsevier 2022-12-16 /pmc/articles/PMC9754762/ /pubmed/36573212 http://dx.doi.org/10.1016/j.nmni.2022.101066 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Orassay, Aliya
Berdigaliyev, Alan
Sadvokassova, Darya
Diassova, Ansal
Amin, Amr
Cao, Wenwen
Xie, Yingqiu
Recent advances on human mpox
title Recent advances on human mpox
title_full Recent advances on human mpox
title_fullStr Recent advances on human mpox
title_full_unstemmed Recent advances on human mpox
title_short Recent advances on human mpox
title_sort recent advances on human mpox
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9754762/
https://www.ncbi.nlm.nih.gov/pubmed/36573212
http://dx.doi.org/10.1016/j.nmni.2022.101066
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