(2R,6R)-hydroxynorketamine acts through GluA1-induced synaptic plasticity to alleviate PTSD-like effects in rat models

Post-traumatic stress disorder (PTSD) is a debilitating mental disorder with high morbidity and great social and economic relevance. However, extant pharmacotherapies of PTSD require long-term use to maintain effectiveness and have enormous side effects. The glutamatergic system, especially the α-am...

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Detalles Bibliográficos
Autores principales: Li, Yu, Du, YaLin, Wang, Chen, Lu, GuoHua, Sun, HongWei, Kong, YuJia, Wang, WeiWen, Lian, Bo, Li, ChangJiang, Wang, Ling, Zhang, XianQiang, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755068/
https://www.ncbi.nlm.nih.gov/pubmed/36532380
http://dx.doi.org/10.1016/j.ynstr.2022.100503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755068/
https://www.ncbi.nlm.nih.gov/pubmed/36532380
http://dx.doi.org/10.1016/j.ynstr.2022.100503

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