The role of growth hormone in assisted reproduction

In contemporary ART, the use of “add-ons” during ovarian stimulation has increased, especially in poor responders. Growth Hormone (GH) is an adjunctive therapy that has been studied extensively in the translational and clinical setting, with an ongoing scientific debate over its effectiveness and op...

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Detalles Bibliográficos
Autores principales: Quaas, Alexander M., Penzias, Alan S., Adashi, Eli Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755199/
https://www.ncbi.nlm.nih.gov/pubmed/36531455
http://dx.doi.org/10.3389/fendo.2022.1055097
Descripción
Sumario:In contemporary ART, the use of “add-ons” during ovarian stimulation has increased, especially in poor responders. Growth Hormone (GH) is an adjunctive therapy that has been studied extensively in the translational and clinical setting, with an ongoing scientific debate over its effectiveness and optimal use. In this review, we aim to provide an overview of the physiologic basis for the use of GH in ART, and to summarize the latest evidence regarding its clinical use, primarily as an adjunct to ovarian stimulation, but also in the IVF lab and with regards to its effects on the endometrium.

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