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Polydactyly-derived allogeneic chondrocyte cell-sheet transplantation with high tibial osteotomy as regenerative therapy for knee osteoarthritis

Allogeneic cell therapies are not fully effective in treating osteoarthritis of the knee (OAK). We recently reported that transplantation of autologous chondrocyte cell-sheets along with open-wedge high tibial osteotomy promoted hyaline cartilage repair in humans. Here we describe our regenerative t...

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Detalles Bibliográficos
Autores principales: Hamahashi, Kosuke, Toyoda, Eriko, Ishihara, Miya, Mitani, Genya, Takagaki, Tomonori, Kaneshiro, Nagatoshi, Maehara, Miki, Takahashi, Takumi, Okada, Eri, Watanabe, Ayako, Nakamura, Yoshihiko, Kato, Reiko, Matoba, Ryo, Takagi, Takehiko, Akutsu, Hidenori, Umezawa, Akihiro, Kobayashi, Hiroyuki, Akamatsu, Tadashi, Yamato, Masayuki, Okano, Teruo, Watanabe, Masahiko, Sato, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755241/
https://www.ncbi.nlm.nih.gov/pubmed/36522336
http://dx.doi.org/10.1038/s41536-022-00272-1