Cargando…

Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view

The heart is one of the most richly innervated organs and the impact of the complex cardiac autonomic network on atrial electrophysiology and arrhythmogenesis, including on atrial ectopy, is widely recognized. The aim of this review is to discuss the main mechanisms involved in atrial ectopic activi...

Descripción completa

Detalles Bibliográficos
Autor principal: Scridon, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755506/
https://www.ncbi.nlm.nih.gov/pubmed/36531175
http://dx.doi.org/10.3389/fphys.2022.1058427
_version_ 1784851435664441344
author Scridon, Alina
author_facet Scridon, Alina
author_sort Scridon, Alina
collection PubMed
description The heart is one of the most richly innervated organs and the impact of the complex cardiac autonomic network on atrial electrophysiology and arrhythmogenesis, including on atrial ectopy, is widely recognized. The aim of this review is to discuss the main mechanisms involved in atrial ectopic activity. An overview of the anatomic and physiological aspects of the cardiac autonomic nervous system is provided as well as a discussion of the main pathophysiological pathways linking autonomic imbalance and atrial ectopic activity. The most relevant data on cardiac neuromodulation strategies are emphasized. Unanswered questions and hotspots for future research are also identified.
format Online
Article
Text
id pubmed-9755506
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-97555062022-12-17 Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view Scridon, Alina Front Physiol Physiology The heart is one of the most richly innervated organs and the impact of the complex cardiac autonomic network on atrial electrophysiology and arrhythmogenesis, including on atrial ectopy, is widely recognized. The aim of this review is to discuss the main mechanisms involved in atrial ectopic activity. An overview of the anatomic and physiological aspects of the cardiac autonomic nervous system is provided as well as a discussion of the main pathophysiological pathways linking autonomic imbalance and atrial ectopic activity. The most relevant data on cardiac neuromodulation strategies are emphasized. Unanswered questions and hotspots for future research are also identified. Frontiers Media S.A. 2022-12-02 /pmc/articles/PMC9755506/ /pubmed/36531175 http://dx.doi.org/10.3389/fphys.2022.1058427 Text en Copyright © 2022 Scridon. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Scridon, Alina
Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title_full Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title_fullStr Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title_full_unstemmed Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title_short Autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
title_sort autonomic imbalance and atrial ectopic activity—a pathophysiological and clinical view
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755506/
https://www.ncbi.nlm.nih.gov/pubmed/36531175
http://dx.doi.org/10.3389/fphys.2022.1058427
work_keys_str_mv AT scridonalina autonomicimbalanceandatrialectopicactivityapathophysiologicalandclinicalview