Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the in vitro ubiquitin transfer cascade

Defining dynamic protein–protein interactions in the ubiquitin conjugation reaction is a challenging research area. Generating peptide aptamers that target components such as ubiquitin itself, E1, E2, or E3 could provide tools to dissect novel features of the enzymatic cascade. Next-generation deep...

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Detalles Bibliográficos
Autores principales: Lisowska, Małgorzata, Lickiss, Fiona, Gil-Mir, Maria, Huart, Anne-Sophie, Trybala, Zuzanna, Way, Luke, Hernychova, Lenka, Krejci, Adam, Muller, Petr, Krejcir, Radovan, Zhukow, Igor, Jurczak, Przemyslaw, Rodziewicz-Motowidło, Sylwia, Ball, Kathryn, Vojtesek, Borivoj, Hupp, Ted, Kalathiya, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755681/
https://www.ncbi.nlm.nih.gov/pubmed/36532480
http://dx.doi.org/10.3389/fmicb.2022.875556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755681/
https://www.ncbi.nlm.nih.gov/pubmed/36532480
http://dx.doi.org/10.3389/fmicb.2022.875556

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