Cargando…

Complex molecular profile of DNA repair genes in epithelial ovarian carcinoma patients with different sensitivity to platinum-based therapy

Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and DNA repair genes are promising targets for novel t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seborova, Karolina, Hlavac, Viktor, Holy, Petr, Bjørklund, Sunniva S., Fleischer, Thomas, Rob, Lukas, Hruda, Martin, Bouda, Jiri, Mrhalova, Marcela, Allah, Mohammad Moufaq Khatar Al Obeed, Vodicka, Pavel, Fiala, Ondrej, Soucek, Pavel, Kristensen, Vessela N., Vodickova, Ludmila, Vaclavikova, Radka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755737/ https://www.ncbi.nlm.nih.gov/pubmed/36531044 http://dx.doi.org/10.3389/fonc.2022.1016958

Ejemplares similares

Whole-exome sequencing of epithelial ovarian carcinomas differing in resistance to platinum therapy
por: Hlaváč, Viktor, et al.
Publicado: (2022)

Non-Coding RNAs as Biomarkers of Tumor Progression and Metastatic Spread in Epithelial Ovarian Cancer
por: Seborova, Karolina, et al.
Publicado: (2021)

Association of ABC gene profiles with time to progression and resistance in ovarian cancer revealed by bioinformatics analyses
por: Seborova, Karolina, et al.
Publicado: (2019)

DNA Repair and Ovarian Carcinogenesis: Impact on Risk, Prognosis and Therapy Outcome
por: Tomasova, Kristyna, et al.
Publicado: (2020)

Non-Coding Polymorphisms in Nucleotide Binding Domain 1 in ABCC1 Gene Associate with Transcript Level and Survival of Patients with Breast Cancer
por: Kunická, Tereza, et al.
Publicado: (2014)

The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes
por: Seborova, Karolina, et al.
Publicado: (2021)

Association of lncRNA and transcriptome intersections with response to targeted therapy in metastatic renal cell carcinoma
por: Tesarova, Tereza, et al.
Publicado: (2023)

ABCB1 Amplicon Contains Cyclic AMP Response Element-Driven TRIP6 Gene in Taxane-Resistant MCF-7 Breast Cancer Sublines
por: Daniel, Petr, et al.
Publicado: (2023)

Gene Expression Profiling Reveals Novel Candidate Markers of Ovarian Carcinoma Intraperitoneal Metastasis
por: Elsnerova, Katerina, et al.
Publicado: (2017)

The Role of Cytochromes P450 and Aldo-Keto Reductases in Prognosis of Breast Carcinoma Patients
por: Hlaváč, Viktor, et al.
Publicado: (2014)

Integrative analysis of mRNA and miRNA expression profiles and somatic variants in oxysterol signaling in early‐stage luminal breast cancer
por: Holý, Petr, et al.
Publicado: (2023)

Role of Genetic Variation in Cytochromes P450 in Breast Cancer Prognosis and Therapy Response
por: Hlaváč, Viktor, et al.
Publicado: (2021)

Role of Genetic Variation in ABC Transporters in Breast Cancer Prognosis and Therapy Response
por: Hlaváč, Viktor, et al.
Publicado: (2020)

Pharmacogenomics to Predict Tumor Therapy Response: A Focus on ATP-Binding Cassette Transporters and Cytochromes P450
por: Hlaváč, Viktor, et al.
Publicado: (2020)

Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases
por: Heczko, Lucie, et al.
Publicado: (2023)

Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model
por: Seborova, Karolina, et al.
Publicado: (2022)

Genetic Susceptibility in Understanding of Pancreatic Ductal Adenocarcinoma Risk: A Decade-Long Effort of the PANDORA Consortium
por: Vodickova, Ludmila, et al.
Publicado: (2022)

ABC Transporters and Their Role in the Neoadjuvant Treatment of Esophageal Cancer
por: Vrana, David, et al.
Publicado: (2018)

Comparison of chromosomal aberrations frequency and polymorphism of GSTs genes in workers occupationally exposed to cytostatics or anaesthetics
por: Mušák, Ľudovít, et al.
Publicado: (2009)

Do GST Polymorphisms Modulate the Frequency of Chromosomal Aberrations in Healthy Subjects?
por: Vodicka, Pavel, et al.
Publicado: (2009)

The Interactions of DNA Repair, Telomere Homeostasis, and p53 Mutational Status in Solid Cancers: Risk, Prognosis, and Prediction
por: Vodicka, Pavel, et al.
Publicado: (2021)

Editorial: Current understanding of genomic and chromosomal instabilities in solid malignancies
por: Vodicka, Pavel, et al.
Publicado: (2023)

Use of Germline Genetic Variability for Prediction of Chemoresistance and Prognosis of Breast Cancer Patients
por: Hlavac, Viktor, et al.
Publicado: (2018)

5′ Untranslated Region Elements Show High Abundance and Great Variability in Homologous ABCA Subfamily Genes
por: Dvorak, Pavel, et al.
Publicado: (2020)

Epigenetic alterations at distal enhancers are linked to proliferation in human breast cancer
por: Ankill, Jørgen, et al.
Publicado: (2022)

DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers
por: Caja, Fabian, et al.
Publicado: (2020)

Laser Capture Microdissection: A Gear for Pancreatic Cancer Research
por: Rao, Bhavana Hemantha, et al.
Publicado: (2022)

TElomeric repeat-containing RNA (TERRA): Physiological functions and relevance in cancer
por: Kroupa, Michal, et al.
Publicado: (2022)

Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes
por: Vymetalkova, Veronika, et al.
Publicado: (2015)

Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
por: Soucek, Pavel, et al.
Publicado: (2004)

A novel c. 204 Ile68Met germline variant in exon 2 of the mutL homolog 1 gene in a colorectal cancer patient
por: VODICKA, PAVEL, et al.
Publicado: (2015)

Local Immune Changes in Early Stages of Inflammation and Carcinogenesis Correlate with the Collagen Scaffold Changes of the Colon Mucosa
por: Čaja, Fabián, et al.
Publicado: (2021)

Downregulation of ABC Transporters in Non-neoplastic Tissues Confers Better Prognosis for Pancreatic and Colorectal Cancer Patients
por: Dvorak, Pavel, et al.
Publicado: (2017)

Effect of occupational exposure to cytostatics and nucleotide excision repair polymorphism on chromosomal aberrations frequency
por: Mušák, L'udovít, et al.
Publicado: (2009)

Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
por: Aure, Miriam Ragle, et al.
Publicado: (2021)

CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence
por: Ambrozkiewicz, Filip, et al.
Publicado: (2022)

Discovery of Long Non-Coding RNA MALAT1 Amplification in Precancerous Colorectal Lesions
por: Siskova, Anna, et al.
Publicado: (2022)

Antioxidant, Anti-Inflammatory, and Multidrug Resistance Modulation Activity of Silychristin Derivatives
por: Viktorová, Jitka, et al.
Publicado: (2019)

A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer
por: Campa, Daniele, et al.
Publicado: (2010)

Single Nucleotide Polymorphisms within Interferon Signaling Pathway Genes Are Associated with Colorectal Cancer Susceptibility and Survival
por: Lu, Shun, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ue4rje51hp7nv67pth5u3klo6k