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Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method

The objective of this study is to construct a multi-department symptom-based automatic diagnosis model. However, it is difficult to establish a model to classify plenty of diseases and collect thousands of disease-symptom datasets simultaneously. Inspired by the thought of “knowledge graph is model”...

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Autores principales: Tian, Yuanyuan, Jin, Yanrui, Li, Zhiyuan, Liu, Jinlei, Liu, Chengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shanghai Jiaotong University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755782/
https://www.ncbi.nlm.nih.gov/pubmed/36540092
http://dx.doi.org/10.1007/s12204-022-2537-z
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author Tian, Yuanyuan
Jin, Yanrui
Li, Zhiyuan
Liu, Jinlei
Liu, Chengliang
author_facet Tian, Yuanyuan
Jin, Yanrui
Li, Zhiyuan
Liu, Jinlei
Liu, Chengliang
author_sort Tian, Yuanyuan
collection PubMed
description The objective of this study is to construct a multi-department symptom-based automatic diagnosis model. However, it is difficult to establish a model to classify plenty of diseases and collect thousands of disease-symptom datasets simultaneously. Inspired by the thought of “knowledge graph is model”, this study proposes to build an experience-infused knowledge model by continuously learning the experiential knowledge from data, and incrementally injecting it into the knowledge graph. Therefore, incremental learning and injection are used to solve the data collection problem, and the knowledge graph is modeled and containerized to solve the large-scale multi-classification problems. First, an entity linking method is designed and a heterogeneous knowledge graph is constructed by graph fusion. Then, an adaptive neural network model is constructed for each dataset, and the data is used for statistical initialization and model training. Finally, the weights and biases of the learned neural network model are updated to the knowledge graph. It is worth noting that for the incremental process, we consider both the data and class increments. We evaluate the diagnostic effectiveness of the model on the current dataset and the anti-forgetting ability on the historical dataset after class increment on three public datasets. Compared with the classical model, the proposed model improves the diagnostic accuracy of the three datasets by 5%, 2%, and 15% on average, respectively. Meanwhile, the model under incremental learning has a better ability to resist forgetting.
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spelling pubmed-97557822022-12-16 Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method Tian, Yuanyuan Jin, Yanrui Li, Zhiyuan Liu, Jinlei Liu, Chengliang J Shanghai Jiaotong Univ Sci Article The objective of this study is to construct a multi-department symptom-based automatic diagnosis model. However, it is difficult to establish a model to classify plenty of diseases and collect thousands of disease-symptom datasets simultaneously. Inspired by the thought of “knowledge graph is model”, this study proposes to build an experience-infused knowledge model by continuously learning the experiential knowledge from data, and incrementally injecting it into the knowledge graph. Therefore, incremental learning and injection are used to solve the data collection problem, and the knowledge graph is modeled and containerized to solve the large-scale multi-classification problems. First, an entity linking method is designed and a heterogeneous knowledge graph is constructed by graph fusion. Then, an adaptive neural network model is constructed for each dataset, and the data is used for statistical initialization and model training. Finally, the weights and biases of the learned neural network model are updated to the knowledge graph. It is worth noting that for the incremental process, we consider both the data and class increments. We evaluate the diagnostic effectiveness of the model on the current dataset and the anti-forgetting ability on the historical dataset after class increment on three public datasets. Compared with the classical model, the proposed model improves the diagnostic accuracy of the three datasets by 5%, 2%, and 15% on average, respectively. Meanwhile, the model under incremental learning has a better ability to resist forgetting. Shanghai Jiaotong University Press 2022-12-16 /pmc/articles/PMC9755782/ /pubmed/36540092 http://dx.doi.org/10.1007/s12204-022-2537-z Text en © Shanghai Jiao Tong University 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Tian, Yuanyuan
Jin, Yanrui
Li, Zhiyuan
Liu, Jinlei
Liu, Chengliang
Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title_full Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title_fullStr Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title_full_unstemmed Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title_short Weighted Heterogeneous Graph-Based Incremental Automatic Disease Diagnosis Method
title_sort weighted heterogeneous graph-based incremental automatic disease diagnosis method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755782/
https://www.ncbi.nlm.nih.gov/pubmed/36540092
http://dx.doi.org/10.1007/s12204-022-2537-z
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AT lizhiyuan weightedheterogeneousgraphbasedincrementalautomaticdiseasediagnosismethod
AT liujinlei weightedheterogeneousgraphbasedincrementalautomaticdiseasediagnosismethod
AT liuchengliang weightedheterogeneousgraphbasedincrementalautomaticdiseasediagnosismethod