Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT

This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which are characterized by ultra-high sensitivity. Thi...

Descripción completa

Detalles Bibliográficos
Autores principales: van Sluis, Joyce, Borra, Ronald, Tsoumpas, Charalampos, van Snick, Johannes H., Roya, Mostafa, ten Hove, Dik, Brouwers, Adrienne H., Lammertsma, Adriaan A., Noordzij, Walter, Dierckx, Rudi A.J.O., Slart, Riemer H.J.A., Glaudemans, Andor W.J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755796/
https://www.ncbi.nlm.nih.gov/pubmed/36527149
http://dx.doi.org/10.1186/s40644-022-00507-w
_version_ 1784851498204659712
author van Sluis, Joyce
Borra, Ronald
Tsoumpas, Charalampos
van Snick, Johannes H.
Roya, Mostafa
ten Hove, Dik
Brouwers, Adrienne H.
Lammertsma, Adriaan A.
Noordzij, Walter
Dierckx, Rudi A.J.O.
Slart, Riemer H.J.A.
Glaudemans, Andor W.J.M.
author_facet van Sluis, Joyce
Borra, Ronald
Tsoumpas, Charalampos
van Snick, Johannes H.
Roya, Mostafa
ten Hove, Dik
Brouwers, Adrienne H.
Lammertsma, Adriaan A.
Noordzij, Walter
Dierckx, Rudi A.J.O.
Slart, Riemer H.J.A.
Glaudemans, Andor W.J.M.
author_sort van Sluis, Joyce
collection PubMed
description This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which are characterized by ultra-high sensitivity. This review not only provides an overview of the published clinical applications using LAFOV PET so far, but also provides insight in clinical applications that are currently under investigation. Apart from the straightforward reduction in acquisition times or administered amount of radiotracer, LAFOV PET also allows for other clinical applications that to date were mostly limited to research, e.g., dual tracer imaging, whole body dynamic PET imaging, omission of CT in serial PET acquisition for repeat imaging, and studying molecular interactions between organ systems. It is expected that this generation of PET systems will significantly advance the field of nuclear medicine and molecular imaging.
format Online
Article
Text
id pubmed-9755796
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-97557962022-12-16 Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT van Sluis, Joyce Borra, Ronald Tsoumpas, Charalampos van Snick, Johannes H. Roya, Mostafa ten Hove, Dik Brouwers, Adrienne H. Lammertsma, Adriaan A. Noordzij, Walter Dierckx, Rudi A.J.O. Slart, Riemer H.J.A. Glaudemans, Andor W.J.M. Cancer Imaging Review This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which are characterized by ultra-high sensitivity. This review not only provides an overview of the published clinical applications using LAFOV PET so far, but also provides insight in clinical applications that are currently under investigation. Apart from the straightforward reduction in acquisition times or administered amount of radiotracer, LAFOV PET also allows for other clinical applications that to date were mostly limited to research, e.g., dual tracer imaging, whole body dynamic PET imaging, omission of CT in serial PET acquisition for repeat imaging, and studying molecular interactions between organ systems. It is expected that this generation of PET systems will significantly advance the field of nuclear medicine and molecular imaging. BioMed Central 2022-12-16 /pmc/articles/PMC9755796/ /pubmed/36527149 http://dx.doi.org/10.1186/s40644-022-00507-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
van Sluis, Joyce
Borra, Ronald
Tsoumpas, Charalampos
van Snick, Johannes H.
Roya, Mostafa
ten Hove, Dik
Brouwers, Adrienne H.
Lammertsma, Adriaan A.
Noordzij, Walter
Dierckx, Rudi A.J.O.
Slart, Riemer H.J.A.
Glaudemans, Andor W.J.M.
Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title_full Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title_fullStr Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title_full_unstemmed Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title_short Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT
title_sort extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity pet/ct
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755796/
https://www.ncbi.nlm.nih.gov/pubmed/36527149
http://dx.doi.org/10.1186/s40644-022-00507-w
work_keys_str_mv AT vansluisjoyce extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT borraronald extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT tsoumpascharalampos extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT vansnickjohannesh extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT royamostafa extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT tenhovedik extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT brouwersadrienneh extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT lammertsmaadriaana extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT noordzijwalter extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT dierckxrudiajo extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT slartriemerhja extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct
AT glaudemansandorwjm extendingtheclinicalcapabilitiesofshortandlonglivedpositronemittingradionuclidesthroughhighsensitivitypetct

Ejemplares similares