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Serum antibody profiling identifies vaccine-induced correlates of protection against aerosolized ricin toxin in rhesus macaques

Inhalation of the biothreat agent, ricin toxin (RT), provokes a localized inflammatory response associated with pulmonary congestion, edema, neutrophil infiltration, and severe acute respiratory distress. The extreme toxicity of RT is the result of the toxin’s B chain (RTB) promoting rapid uptake in...

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Detalles Bibliográficos
Autores principales: Roy, Chad J., Ehrbar, Dylan, Van Slyke, Greta, Doering, Jennifer, Didier, Peter J., Doyle-Meyers, Lara, Donini, Oreola, Vitetta, Ellen S., Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755799/
https://www.ncbi.nlm.nih.gov/pubmed/36526642
http://dx.doi.org/10.1038/s41541-022-00582-x

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