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Serum antibody profiling identifies vaccine-induced correlates of protection against aerosolized ricin toxin in rhesus macaques
Inhalation of the biothreat agent, ricin toxin (RT), provokes a localized inflammatory response associated with pulmonary congestion, edema, neutrophil infiltration, and severe acute respiratory distress. The extreme toxicity of RT is the result of the toxin’s B chain (RTB) promoting rapid uptake in...
Autores principales: | Roy, Chad J., Ehrbar, Dylan, Van Slyke, Greta, Doering, Jennifer, Didier, Peter J., Doyle-Meyers, Lara, Donini, Oreola, Vitetta, Ellen S., Mantis, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755799/ https://www.ncbi.nlm.nih.gov/pubmed/36526642 http://dx.doi.org/10.1038/s41541-022-00582-x |
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