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A genetically modified Plasmodium berghei parasite as a surrogate for whole-sporozoite vaccination against P. vivax malaria

Two malaria parasite species, Plasmodium falciparum (Pf) and P. vivax (Pv) are responsible for most of the disease burden caused by malaria. Vaccine development against this disease has focused mainly on Pf. Whole-sporozoite (WSp) vaccination, targeting pre-erythrocytic (PE) parasite stages, is a pr...

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Detalles Bibliográficos
Autores principales: Moita, Diana, Maia, Teresa G., Duarte, Miguel, Andrade, Carolina M., Albuquerque, Inês S., Dwivedi, Ankit, Silva, Joana C., González-Céron, Lilia, Janse, Chris J., Mendes, António M., Prudêncio, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755804/
https://www.ncbi.nlm.nih.gov/pubmed/36526627
http://dx.doi.org/10.1038/s41541-022-00585-8