Comparing the applications of machine learning, PBPK, and population pharmacokinetic models in pharmacokinetic drug–drug interaction prediction

The gold‐standard approach for modeling pharmacokinetic mediated drug–drug interactions is the use of physiologically‐based pharmacokinetic modeling and population pharmacokinetics. However, these models require extensive amounts of drug‐specific data generated from a wide variety of in vitro and in...

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Detalles Bibliográficos
Autores principales: Gill, Jaidip, Moullet, Marie, Martinsson, Anton, Miljković, Filip, Williamson, Beth, Arends, Rosalinda H., Pilla Reddy, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755922/
https://www.ncbi.nlm.nih.gov/pubmed/36176050
http://dx.doi.org/10.1002/psp4.12870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755922/
https://www.ncbi.nlm.nih.gov/pubmed/36176050
http://dx.doi.org/10.1002/psp4.12870

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