Cargando…

A perspective on the current use of the phase distribution model for predicting milk‐to‐plasma drug concentration ratio

The phase distribution model, proposed by Atkinson and Begg in 1990, has been widely used for predicting breastmilk‐to‐plasma drug concentration ratio. However, misrepresentations of the equations have been noted in recent publications. In this perspective, we revisit the derivation of the equations...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Mian, Sychterz, Caroline, Chang, Ming, Huang, Lu, Schmidt, Brian J., Gaohua, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755927/
https://www.ncbi.nlm.nih.gov/pubmed/36181346
http://dx.doi.org/10.1002/psp4.12865