Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma

Relapse is the leading cause of death in patients with medulloblastoma, the most common malignant pediatric brain tumor. A better understanding of the mechanisms underlying recurrence could lead to more effective therapies for targeting tumor relapses. Here, we observed that SOX9, a transcription fa...

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Detalles Bibliográficos
Autores principales: Borgenvik, Anna, Holmberg, Karl O., Bolin, Sara, Zhao, Miao, Savov, Vasil, Rosén, Gabriela, Hutter, Sonja, Garancher, Alexandra, Rahmanto, Aldwin Suryo, Bergström, Tobias, Olsen, Thale Kristin, Mainwaring, Oliver J., Sattanino, Damiana, Verbaan, Annemieke D., Rusert, Jessica M., Sundström, Anders, Bravo, Mar Ballester, Dang, Yonglong, Wenz, Amelie S., Richardson, Stacey, Fotaki, Grammatiki, Hill, Rebecca M., Dubuc, Adrian M., Kalushkova, Antonia, Remke, Marc, Čančer, Matko, Jernberg-Wiklund, Helena, Giraud, Géraldine, Chen, Xingqi, Taylor, Michael D., Sangfelt, Olle, Clifford, Steven C., Schüller, Ulrich, Wechsler-Reya, Robert J., Weishaupt, Holger, Swartling, Fredrik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Tumor Biology and Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9755969/
https://www.ncbi.nlm.nih.gov/pubmed/36219398
http://dx.doi.org/10.1158/0008-5472.CAN-22-2108

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