Cargando…

Pioglitazone modulates immune activation and ameliorates inflammation induced by injured renal tubular epithelial cells via PPARγ/miRNA‑124/STAT3 signaling

Acute kidney injury (AKI) is commonly a result of renal ischemia reperfusion injury (IRI), which produces clinical complications characterized by the rapid deterioration of renal function, leading to chronic kidney disease and increases the risk of morbidity and mortality. Currently, only supportive...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Gazzar, Walaa Bayoumie, Allam, Mona Maher, Shaltout, Sherif Ahmed, Mohammed, Lina Abdelhady, Sadek, Ashraf Mohamed, Nasr, Hend Elsayed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756109/ https://www.ncbi.nlm.nih.gov/pubmed/36544854 http://dx.doi.org/10.3892/br.2022.1584

Ejemplares similares

Effect of Allopregnanolone on Spatial Memory and Synaptic Proteins in Animal Model of Metabolic Syndrome
por: Amin, Shaimaa Nasr, et al.
Publicado: (2021)

The PPARγ agonist pioglitazone prevents TGF-β induced renal fibrosis by repressing EGR-1 and STAT3
por: Németh, Ágnes, et al.
Publicado: (2019)

STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation
por: Li, Jianzhong, et al.
Publicado: (2022)

Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity
por: Jacques, Vincent, et al.
Publicado: (2021)

Combined saline and vildagliptin induced M2 macrophage polarization in hepatic injury induced by acute kidney injury
por: Amin, Shaimaa N., et al.
Publicado: (2023)

The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
por: Swanson, Christine R, et al.
Publicado: (2011)

Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone
por: Syversen, Unni, et al.
Publicado: (2009)

Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone
por: Lamounier, Rodrigo N, et al.
Publicado: (2013)

Effects of Pioglitazone Mediated Activation of PPAR-γ on CIDEC and Obesity Related Changes in Mice
por: Shamsi, Bilal Haider, et al.
Publicado: (2014)

Diet Modifies Pioglitazone's Influence on Hepatic PPARγ-Regulated Mitochondrial Gene Expression
por: Kulkarni, Sakil, et al.
Publicado: (2020)

Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR
por: Wang, Zhongxia, et al.
Publicado: (2016)

Structures of PPARγ complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs
por: Lee, Min A, et al.
Publicado: (2017)

The Pioglitazone Trek via Human PPAR Gamma: From Discovery to a Medicine at the FDA and Beyond
por: Devchand, Pallavi R., et al.
Publicado: (2018)

Carvacrol and PPARγ agonist, pioglitazone, affects inhaled paraquat-induced lung injury in rats
por: Amin, Fatemeh, et al.
Publicado: (2021)

Pioglitazone, a PPAR-y agonist, as one of the new therapeutic candidates for C3 glomerulopathy
por: Balestra, Elia, et al.
Publicado: (2023)

Melatonin Alleviates Intestinal Barrier Damaging Effects Induced by Polyethylene Microplastics in Albino Rats
por: El Gazzar, Walaa Bayoumie, et al.
Publicado: (2023)

Effects of PPARγ Agonist Pioglitazone on Redox-Sensitive Cellular Signaling in Young Spontaneously Hypertensive Rats
por: Dovinová, Ima, et al.
Publicado: (2013)

Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs
por: Helmy, Mai M., et al.
Publicado: (2015)

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial
por: Anderson, J. R., et al.
Publicado: (2016)

Pioglitazone, a PPAR-γ Activator, Stimulates BK(Ca) but Suppresses IK(M) in Hippocampal Neurons
por: Chen, Tsang-Shan, et al.
Publicado: (2018)

Corrigendum to “Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR”
por: Wang, Zhongxia, et al.
Publicado: (2019)

Post-treatment with the PPAR-γ agonist pioglitazone inhibits inflammation and bacterial growth during Klebsiella pneumonia
por: Ramirez-Moral, Ivan, et al.
Publicado: (2021)

Alteration of PPAR‐GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leukemia patients and the promising anticancer effects of PPARγ stimulation using pioglitazone on AML cells
por: Esmaeili, Shadi, et al.
Publicado: (2021)

PIAS1 alleviates diabetic peripheral neuropathy through SUMOlation of PPAR-γ and miR-124-induced downregulation of EZH2/STAT3
por: Hou, Zixin, et al.
Publicado: (2021)

Viral manipulation of STAT3: Evade, exploit, and injure
por: Roca Suarez, Armando Andres, et al.
Publicado: (2018)

The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
por: Gray, Elizabeth, et al.
Publicado: (2012)

Ischemia reperfusion-induced metastasis is resistant to PPARγ agonist pioglitazone in a murine model of colon cancer
por: Tashiro, Yoshihiko, et al.
Publicado: (2020)

Retraction Note: Carvacrol and PPARγ agonist, pioglitazone, affects inhaled paraquat-induced lung injury in rats
por: Amin, Fatemeh, et al.
Publicado: (2022)

The PPAR-γ Agonist Pioglitazone Modulates Proliferation and Migration in HUVEC, HAOSMC and Human Arteriovenous Fistula-Derived Cells
por: Ciavarella, Carmen, et al.
Publicado: (2023)

PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients
por: Di Donfrancesco, Alessia, et al.
Publicado: (2023)

The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats
por: Stunes, Astrid K, et al.
Publicado: (2011)

Pioglitazone Ameliorates Gentamicin Ototoxicity by Affecting the TLR and STAT Pathways in the Early Postnatal Organ of Corti
por: Sekulic-Jablanovic, Marijana, et al.
Publicado: (2020)

Prophylactic and Ameliorative Effects of PPAR-γ Agonist Pioglitazone in Improving Oxidative Stress, Germ Cell Apoptosis and Inflammation in Gentamycin-Induced Testicular Damage in Adult Male Albino Rats
por: El-Sayed, Karima, et al.
Publicado: (2022)

Pioglitazone Reduces β Amyloid Levels via Inhibition of PPARγ Phosphorylation in a Neuronal Model of Alzheimer’s Disease
por: Quan, Qiankun, et al.
Publicado: (2019)

PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients
por: Yemchenko, Ya. O., et al.
Publicado: (2020)

Relationship between PPARα activation and NO on proximal tubular Na(+ )transport in the rat
por: Newaz, Mohammad A, et al.
Publicado: (2004)

SAT-LB124 Phosphatidylcholine Transfer Protein Interacts With PPARδ to Modulate Activity
por: Druzak, Samuel Adam, et al.
Publicado: (2020)

Pioglitazone Mediates Cardiac Progenitor Formation through Increasing ROS Levels
por: Baharlooie, Maryam, et al.
Publicado: (2022)

The mechanism of blood concentrations of the Shenqi pill repairing injured epithelial cells of renal tubular in vitro
por: Huang, Fei, et al.
Publicado: (2017)

Hibiscus attenuates renovascular hypertension–induced aortic remodeling dose dependently: the oxidative stress role and Ang II/cyclophilin A/ERK1/2 signaling
por: ShamsEldeen, Asmaa Mohammed, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4mgsme03qde8t8hk4hcemu4q4f