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Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging

SMC complexes play key roles in genome maintenance, where they ensure efficient genome replication and segregation. The SMC complex Smc5/6 is a crucial player in DNA replication and repair, yet many molecular features that determine its roles are unclear. Here, we use single-molecule microscopy to i...

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Detalles Bibliográficos
Autores principales: Tanasie, Nicoleta-Loredana, Gutiérrez-Escribano, Pilar, Jaklin, Sigrun, Aragon, Luis, Stigler, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756111/
https://www.ncbi.nlm.nih.gov/pubmed/36476856
http://dx.doi.org/10.1016/j.celrep.2022.111778