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Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging
SMC complexes play key roles in genome maintenance, where they ensure efficient genome replication and segregation. The SMC complex Smc5/6 is a crucial player in DNA replication and repair, yet many molecular features that determine its roles are unclear. Here, we use single-molecule microscopy to i...
Autores principales: | Tanasie, Nicoleta-Loredana, Gutiérrez-Escribano, Pilar, Jaklin, Sigrun, Aragon, Luis, Stigler, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756111/ https://www.ncbi.nlm.nih.gov/pubmed/36476856 http://dx.doi.org/10.1016/j.celrep.2022.111778 |
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