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Access to medicines for children in China

Access to essential medicines for children is a big challenge, particularly in low-income and middle-income countries. In China, the average availability of essential medicines for children is 1.6%–46.5%. The availability of generics was generally higher than original brands in public hospitals and...

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Autores principales: Chen, Zhe, Li, Siyu, Choonara, Imti, Zou, Kun, Zeng, Linan, Huang, Liang, Jia, Zhi-Jun, Cheng, Guo, Jiang, Yongmu, Tang, Yong, Zhao, Shaoyang, Zhang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756215/
https://www.ncbi.nlm.nih.gov/pubmed/36645793
http://dx.doi.org/10.1136/bmjpo-2022-001635
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author Chen, Zhe
Li, Siyu
Choonara, Imti
Zou, Kun
Zeng, Linan
Huang, Liang
Jia, Zhi-Jun
Cheng, Guo
Jiang, Yongmu
Tang, Yong
Zhao, Shaoyang
Zhang, Lingli
author_facet Chen, Zhe
Li, Siyu
Choonara, Imti
Zou, Kun
Zeng, Linan
Huang, Liang
Jia, Zhi-Jun
Cheng, Guo
Jiang, Yongmu
Tang, Yong
Zhao, Shaoyang
Zhang, Lingli
author_sort Chen, Zhe
collection PubMed
description Access to essential medicines for children is a big challenge, particularly in low-income and middle-income countries. In China, the average availability of essential medicines for children is 1.6%–46.5%. The availability of generics was generally higher than original brands in public hospitals and the prices of generics were relatively lower and more reasonable (generics: availability, 27.3%–46.5%, prices, 0.52–4.28 times the international reference prices; original brands: 1.6%–33.0%, 2.59–11.38 times the international reference prices). In terms of affordability of medicines for children, generics were more affordable than original brands and tablets/capsules were more affordable than injections. Most commonly used anti-infective medicines (such as amoxicillin capsule, azithromycin tablet, cefuroxime tablet) and antipyretics (such as ibuprofen suspension) were relatively affordable. Six commonly used medicines in paediatrics, including amoxicillin/clavulanic acid, beclomethasone, cefazolin, ceftazidime, ceftriaxone, cyclosporine were unaffordable. Since August 2011, China has successively issued several policies to ensure the accessibility of medicines for children, covering research and development, production, procurement and prices of medicines. The accessibility of medicines for children has been partially improved, but still needs continuous improvement.
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spelling pubmed-97562152022-12-17 Access to medicines for children in China Chen, Zhe Li, Siyu Choonara, Imti Zou, Kun Zeng, Linan Huang, Liang Jia, Zhi-Jun Cheng, Guo Jiang, Yongmu Tang, Yong Zhao, Shaoyang Zhang, Lingli BMJ Paediatr Open Review Access to essential medicines for children is a big challenge, particularly in low-income and middle-income countries. In China, the average availability of essential medicines for children is 1.6%–46.5%. The availability of generics was generally higher than original brands in public hospitals and the prices of generics were relatively lower and more reasonable (generics: availability, 27.3%–46.5%, prices, 0.52–4.28 times the international reference prices; original brands: 1.6%–33.0%, 2.59–11.38 times the international reference prices). In terms of affordability of medicines for children, generics were more affordable than original brands and tablets/capsules were more affordable than injections. Most commonly used anti-infective medicines (such as amoxicillin capsule, azithromycin tablet, cefuroxime tablet) and antipyretics (such as ibuprofen suspension) were relatively affordable. Six commonly used medicines in paediatrics, including amoxicillin/clavulanic acid, beclomethasone, cefazolin, ceftazidime, ceftriaxone, cyclosporine were unaffordable. Since August 2011, China has successively issued several policies to ensure the accessibility of medicines for children, covering research and development, production, procurement and prices of medicines. The accessibility of medicines for children has been partially improved, but still needs continuous improvement. BMJ Publishing Group 2022-12-15 /pmc/articles/PMC9756215/ /pubmed/36645793 http://dx.doi.org/10.1136/bmjpo-2022-001635 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Chen, Zhe
Li, Siyu
Choonara, Imti
Zou, Kun
Zeng, Linan
Huang, Liang
Jia, Zhi-Jun
Cheng, Guo
Jiang, Yongmu
Tang, Yong
Zhao, Shaoyang
Zhang, Lingli
Access to medicines for children in China
title Access to medicines for children in China
title_full Access to medicines for children in China
title_fullStr Access to medicines for children in China
title_full_unstemmed Access to medicines for children in China
title_short Access to medicines for children in China
title_sort access to medicines for children in china
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756215/
https://www.ncbi.nlm.nih.gov/pubmed/36645793
http://dx.doi.org/10.1136/bmjpo-2022-001635
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