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Oncogenic KRAS alters splicing factor phosphorylation and alternative splicing in lung cancer

BACKGROUND: Alternative RNA splicing is widely dysregulated in cancers including lung adenocarcinoma, where aberrant splicing events are frequently caused by somatic splice site mutations or somatic mutations of splicing factor genes. However, the majority of mis-splicing in cancers is unexplained b...

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Detalles Bibliográficos
Autores principales:	Lo, April, McSharry, Maria, Berger, Alice H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756471/ https://www.ncbi.nlm.nih.gov/pubmed/36522653 http://dx.doi.org/10.1186/s12885-022-10311-1

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