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PCSK9 inhibition and cholesterol homeostasis in insulin producing β-cells

Low-density lipoprotein cholesterol (LDL-C) plays a central role in the pathology of atherosclerotic cardiovascular disease. For decades, the gold standard for LDL-C lowering have been statins, although these drugs carry a moderate risk for the development of new-onset diabetes. The inhibitors of pr...

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Detalles Bibliográficos
Autores principales: Päth, Günter, Perakakis, Nikolaos, Mantzoros, Christos S., Seufert, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9756761/
https://www.ncbi.nlm.nih.gov/pubmed/36527064
http://dx.doi.org/10.1186/s12944-022-01751-6